LymphedemaV1, Main, Exploration, bibRecord, 007377

Podoconiosis: non-infectious geochemical elephantiasis

Identifieur interne : 007377 ( Main/Exploration ); précédent : 007376; suivant : 007378

Podoconiosis: non-infectious geochemical elephantiasis

Auteurs : Gail Davey [Éthiopie] ; Fasil Tekola [Éthiopie] ; Melanie J. Newport [Royaume-Uni]

Source :

Transactions of The Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 2007-12.

RBID : ISTEX:CAE4E5E09403AA4FA965C81B33A485D1BCFA5439

Descripteurs français

KwdFr :
- Diagnostic différentiel, Femelle, Humains, Mâle, Santé en zone rurale, Sol, Éléphantiasis (), Éléphantiasis (anatomopathologie), Éléphantiasis (diagnostic).
MESH :
- anatomopathologie : Éléphantiasis.
- diagnostic : Éléphantiasis.
- Diagnostic différentiel, Femelle, Humains, Mâle, Santé en zone rurale, Sol, Éléphantiasis.
Pascal (Inist)
- Article synthèse, Eléphantiasis, Homme, Infection, Lymphoedème, Médecine tropicale, Podoconiose.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Diagnosis, Differential, Elephantiasis, Elephantiasis (diagnosis), Elephantiasis (pathology), Elephantiasis (prevention & control), Female, Geochemical, Human, Humans, Infection, Lymphedema, Male, Non-filarial elephantiasis, Podoconiosis, Review, Rural Health, Soil, Tropical medicine.
MESH :
- chemical : Soil.
- diagnosis : Elephantiasis.
- pathology : Elephantiasis.
- prevention & control : Elephantiasis.
- Diagnosis, Differential, Female, Humans, Male, Rural Health.

Abstract

This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.

Url:

https://api.istex.fr/document/CAE4E5E09403AA4FA965C81B33A485D1BCFA5439/fulltext/pdf

DOI: 10.1016/j.trstmh.2007.08.013

Affiliations:

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<front><div type="abstract">This article reviews peer-reviewed publications and book chapters on the history, epidemiology, genetics, ecology, pathogenesis, pathology and management of podoconiosis (endemic non-filarial elephantiasis). Podoconiosis is a non-infectious geochemical elephantiasis caused by exposure of bare feet to irritant alkalic clay soils. It is found in at least 10 countries in tropical Africa, Central America and northwest India, where such soils coexist with high altitude, high seasonal rainfall and low income. Podoconiosis develops in men and women working barefoot on irritant soils, with signs becoming apparent in most patients by the third decade of life. Colloid-sized silicate particles appear to enter through the skin, are taken up into macrophages in the lower limb lymphatics and cause endolymphangitis and obliteration of the lymphatic lumen. Genetic studies provide evidence for high heritability of susceptibility to podoconiosis. The economic burden is significant in affected areas dependent on subsistence farming. Podoconiosis is unique in being an entirely preventable non-communicable disease. Primary prevention entails promoting use of footwear in areas of irritant soil; early stages are reversible given good foot hygiene, but late stages result in considerable economic and social difficulties, and require extended periods of elevation and occasionally nodulectomy.</div>
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Podoconiosis: non-infectious geochemical elephantiasis

Podoconiosis: non-infectious geochemical elephantiasis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur le lymphœdème
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